STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB81726.1Aconitase; InterPro IPR001030:IPR000573:IPR018136:IPR006250; COGs: COG1048 Aconitase A; KEGG: afr:AFE_0423 aconitate hydratase; SPTR: A3ERT8 Aconitase A; PFAM: aconitate hydratase domain protein; TIGRFAM: aconitate hydratase. (641 aa)    
Predicted Functional Partners:
SMB81741.1
Citrate synthase; InterPro IPR002020:IPR019810; COGs: COG0372 Citrate synthase; KEGG: noc:Noc_2628 methylcitrate synthase; SPTR: Q974S5 Citrate synthase; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; Belongs to the citrate synthase family.
 
 0.995
SMB79105.1
Isocitrate dehydrogenase (NADP); InterPro IPR001804:IPR019818:IPR004790; COGs: COG0538 Isocitrate dehydrogenase; KEGG: dps:DP0778 isocitrate dehydrogenase; SPTR: A5KQ84 Putative uncharacterized protein; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NADP(+)); TIGRFAM: isocitrate dehydrogenase, NADP-dependent; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.984
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 0.979
SMB83330.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase; InterPro IPR001450:IPR019752:IPR019456:IPR002880:IPR017900:IPR0118 95; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; KEGG: dvl:Dvul_0348 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein; SPTR: A1HPH8 Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Pyruvate-flavodoxin oxidoreduct [...]
  
 
 0.935
SMB92876.1
Superoxide dismutase, Fe-Mn family; InterPro IPR019832; COGs: COG0605 Superoxide dismutase; KEGG: scl:sce0071 hypothetical protein; SPTR: Q9HM56 Probable Fe-superoxide dismutase (Sod); PFAM: Manganese/iron superoxide dismutase-like.
   
 
 0.904
rpmB
InterPro IPR001383; COGs: COG0227 Ribosomal protein L28; KEGG: gme:Gmet_2323 50S ribosomal protein L28; SPTR: B0TGU2 50S ribosomal protein L28; PFAM: ribosomal protein L28; TIGRFAM: ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
   
   0.865
rplS
LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
 
 0.865
rpmF
LSU ribosomal protein L32P; InterPro IPR002677; KEGG: gur:Gura_1873 50S ribosomal protein L32; SPTR: Q24U37 50S ribosomal protein L32; PFAM: ribosomal L32p protein; TIGRFAM: ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
   
   0.859
rpmJ
LSU ribosomal protein L36P; InterPro IPR000473; KEGG: pca:Pcar_0724 ribosomal protein L36; SPTR: Q8ETW1 50S ribosomal protein L36; PFAM: ribosomal protein L36; TIGRFAM: ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family.
   
 
 0.857
rnc
RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
   
 
 0.854
Your Current Organism:
Desulfonispora thiosulfatigenes
NCBI taxonomy Id: 656914
Other names: D. thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes str. DSM 11270, Desulfonispora thiosulfatigenes strain DSM 11270
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.