STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMB91310.14-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis; InterPro IPR002818:IPR006287; COGs: COG0693 Putative intracellular protease/amidase; KEGG: cco:CCC13826_0481 DJ-1 family protein; SPTR: A5LQI4 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis protein, putative; PFAM: ThiJ/PfpI domain protein; TIGRFAM: DJ-1 family protein. (186 aa)    
Predicted Functional Partners:
rpsJ
SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
   0.773
rplN
LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
    
   0.740
SMB95089.1
Acetoin utilization deacetylase AcuC; InterPro IPR000286; COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; KEGG: sat:SYN_02870 histone deacetylase domain-containing protein; SPTR: Q467W5 Histone deacetylase; PFAM: histone deacetylase superfamily; PRIAM: Histone deacetylase.
    
  0.724
SMB87450.1
D-3-phosphoglycerate dehydrogenase; InterPro IPR006139:IPR002912:IPR006140:IPR006236; COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; KEGG: sat:SYN_00123 D-3-phosphoglycerate dehydrogenase; SPTR: A1HUC3 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; amino acid-binding ACT domain protein; PRIAM: Phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase.
  
 
  0.716
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
   
   0.686
rplE
LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
   
 
 0.668
rpsS
SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
   0.665
SMB92264.1
Tetratricopeptide repeat-containing protein; InterPro IPR001440:IPR013105:IPR019734:IPR013026; COGs: COG3063 Tfp pilus assembly protein PilF; KEGG: TPR Domain containing protein; SPTR: Q24CU0 TPR Domain containing protein; SMART: Tetratricopeptide repeat; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein.
  
 
 0.642
SMB89984.1
2-enoate reductase; InterPro IPR013027:IPR000103:IPR001327:IPR001155; COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; KEGG: vfm:VFMJ11_A0422 NADH oxidase; SPTR: O29794 NADH oxidase (NoxB-1); PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.612
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.607
Your Current Organism:
Desulfonispora thiosulfatigenes
NCBI taxonomy Id: 656914
Other names: D. thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes DSM 11270, Desulfonispora thiosulfatigenes str. DSM 11270, Desulfonispora thiosulfatigenes strain DSM 11270
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