STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mzrAModulator protein; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR. (142 aa)    
Predicted Functional Partners:
KKF36229.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.907
KKF36234.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.856
KKF36233.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.849
envZ
Osmolarity sensor protein; Membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.807
rcsD
tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
  
 
   0.805
aaeX
Transporter; Membrane protein AaeX; the gene is a member of the aaeXAB operon; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.774
ompX
Membrane protein; OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.773
KKF36228.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.773
KKF34592.1
DNA replication terminus site-binding protein; Binds to DNA replication terminator sequences to prevent passage of replication forks; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.772
KKF34206.1
Hha toxicity attenuator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.772
Your Current Organism:
Erwinia tracheiphila
NCBI taxonomy Id: 65700
Other names: ATCC 33245, Bacillus tracheiphilus, Bacterium tracheiphilus, CFBP 2355, CIP 105205, DSM 21139, E. tracheiphila, Erwinia amylovora var. tracheiphila, ICMP 5845, LMG 2707, LMG 2906, LMG:2707, LMG:2906, NCPPB 2452
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