| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KKF36035.1 | KKF36486.1 | SY86_12350 | SY86_15250 | DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | DSBA oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.691 |
| KKF36035.1 | KKF36864.1 | SY86_12350 | SY86_17840 | DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.723 |
| KKF36035.1 | ftsN | SY86_12350 | SY86_18320 | DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | Cell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. | 0.783 |
| KKF36035.1 | lptE | SY86_12350 | SY86_00815 | DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | LPS biosynthesis protein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | 0.431 |
| KKF36035.1 | tolB | SY86_12350 | SY86_01120 | DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | Translocation protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. | 0.671 |
| KKF36035.1 | zapB | SY86_12350 | SY86_18290 | DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | Septal ring assembly protein ZapB; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.768 |
| KKF36486.1 | KKF36035.1 | SY86_15250 | SY86_12350 | DSBA oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | 0.691 |
| KKF36486.1 | KKF36488.1 | SY86_15250 | SY86_15260 | DSBA oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.764 |
| KKF36486.1 | KKF36864.1 | SY86_15250 | SY86_17840 | DSBA oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.757 |
| KKF36486.1 | dipZ | SY86_15250 | SY86_14005 | DSBA oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiol:disulfide interchange protein precursor; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. | 0.870 |
| KKF36486.1 | dsbB | SY86_15250 | SY86_01825 | DSBA oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. | 0.970 |
| KKF36486.1 | ftsN | SY86_15250 | SY86_18320 | DSBA oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. | 0.768 |
| KKF36486.1 | lptE | SY86_15250 | SY86_00815 | DSBA oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | LPS biosynthesis protein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | 0.706 |
| KKF36486.1 | srkA | SY86_15250 | SY86_15255 | DSBA oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine/threonine protein kinase; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. | 0.909 |
| KKF36486.1 | tolB | SY86_15250 | SY86_01120 | DSBA oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Translocation protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. | 0.697 |
| KKF36486.1 | zapB | SY86_15250 | SY86_18290 | DSBA oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Septal ring assembly protein ZapB; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.747 |
| KKF36488.1 | KKF36486.1 | SY86_15260 | SY86_15250 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DSBA oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.764 |
| KKF36488.1 | srkA | SY86_15260 | SY86_15255 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine/threonine protein kinase; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. | 0.621 |
| KKF36488.1 | zapB | SY86_15260 | SY86_18290 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Septal ring assembly protein ZapB; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.662 |
| KKF36864.1 | KKF36035.1 | SY86_17840 | SY86_12350 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. | 0.723 |