| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KKF34278.1 | KKF34401.1 | SY86_25220 | SY86_23810 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0352 family. | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | 0.684 |
| KKF34278.1 | KKF37368.1 | SY86_25220 | SY86_21295 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0352 family. | Lipoprotein NlpI; May be involved in cell division. | 0.614 |
| KKF34278.1 | lptC | SY86_25220 | SY86_21100 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0352 family. | Lipopolysaccharide transporter; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.704 |
| KKF34278.1 | proQ | SY86_25220 | SY86_10880 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0352 family. | Prop expression regulator; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family. | 0.753 |
| KKF34278.1 | rraB | SY86_25220 | SY86_21430 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0352 family. | Regulator; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.721 |
| KKF34401.1 | KKF34278.1 | SY86_23810 | SY86_25220 | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0352 family. | 0.684 |
| KKF34401.1 | KKF37368.1 | SY86_23810 | SY86_21295 | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | Lipoprotein NlpI; May be involved in cell division. | 0.642 |
| KKF34401.1 | lptC | SY86_23810 | SY86_21100 | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | Lipopolysaccharide transporter; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. | 0.769 |
| KKF34401.1 | proQ | SY86_23810 | SY86_10880 | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | Prop expression regulator; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family. | 0.689 |
| KKF34401.1 | rraB | SY86_23810 | SY86_21430 | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | Regulator; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.685 |
| KKF35817.1 | KKF37368.1 | SY86_10885 | SY86_21295 | Carboxy-terminal protease; Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S41A family. | Lipoprotein NlpI; May be involved in cell division. | 0.933 |
| KKF35817.1 | proQ | SY86_10885 | SY86_10880 | Carboxy-terminal protease; Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S41A family. | Prop expression regulator; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family. | 0.924 |
| KKF37159.1 | KKF37368.1 | SY86_19935 | SY86_21295 | Intracellular growth attenuator protein igaA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Lipoprotein NlpI; May be involved in cell division. | 0.625 |
| KKF37159.1 | KKF37935.1 | SY86_19935 | SY86_20940 | Intracellular growth attenuator protein igaA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.773 |
| KKF37159.1 | rraB | SY86_19935 | SY86_21430 | Intracellular growth attenuator protein igaA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Regulator; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.440 |
| KKF37368.1 | KKF34278.1 | SY86_21295 | SY86_25220 | Lipoprotein NlpI; May be involved in cell division. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0352 family. | 0.614 |
| KKF37368.1 | KKF34401.1 | SY86_21295 | SY86_23810 | Lipoprotein NlpI; May be involved in cell division. | anti-RNA polymerase sigma factor SigE; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic protea [...] | 0.642 |
| KKF37368.1 | KKF35817.1 | SY86_21295 | SY86_10885 | Lipoprotein NlpI; May be involved in cell division. | Carboxy-terminal protease; Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S41A family. | 0.933 |
| KKF37368.1 | KKF37159.1 | SY86_21295 | SY86_19935 | Lipoprotein NlpI; May be involved in cell division. | Intracellular growth attenuator protein igaA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.625 |
| KKF37368.1 | KKF37935.1 | SY86_21295 | SY86_20940 | Lipoprotein NlpI; May be involved in cell division. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.622 |