node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KKF37490.1 | KKF37955.1 | SY86_22210 | SY86_22215 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Multicopper oxidase; Laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.685 |
KKF37955.1 | KKF37490.1 | SY86_22215 | SY86_22210 | Multicopper oxidase; Laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.685 |
KKF37955.1 | copA | SY86_22215 | SY86_23965 | Multicopper oxidase; Laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; Derived by automated computational analysis using gene prediction method: Protein Homology. | Copper-transporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.616 |
KKF37955.1 | cueR | SY86_22215 | SY86_08890 | Multicopper oxidase; Laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Activator of copper-responsive regulon genes; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.745 |
KKF37955.1 | rpoD | SY86_22215 | SY86_21620 | Multicopper oxidase; Laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.667 |
KKF37955.1 | tatB | SY86_22215 | SY86_15350 | Multicopper oxidase; Laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; Derived by automated computational analysis using gene prediction method: Protein Homology. | Translocase; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.715 |
KKF37955.1 | tatC | SY86_22215 | SY86_15345 | Multicopper oxidase; Laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; Derived by automated computational analysis using gene prediction method: Protein Homology. | Twin-arginine protein translocation system subunit TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.702 |
KKF37955.1 | topB | SY86_22215 | SY86_01955 | Multicopper oxidase; Laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | 0.613 |
KKF37955.1 | uvrB | SY86_22215 | SY86_05955 | Multicopper oxidase; Laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.613 |
KKF37955.1 | xerC | SY86_22215 | SY86_15495 | Multicopper oxidase; Laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; Derived by automated computational analysis using gene prediction method: Protein Homology. | Site-specific tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifical [...] | 0.613 |
KKF37955.1 | xerD | SY86_22215 | SY86_08415 | Multicopper oxidase; Laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; Derived by automated computational analysis using gene prediction method: Protein Homology. | Site-specific tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifical [...] | 0.613 |
copA | KKF37955.1 | SY86_23965 | SY86_22215 | Copper-transporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Multicopper oxidase; Laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.616 |
copA | cueR | SY86_23965 | SY86_08890 | Copper-transporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Activator of copper-responsive regulon genes; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.536 |
copA | uvrB | SY86_23965 | SY86_05955 | Copper-transporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.482 |
cueR | KKF37955.1 | SY86_08890 | SY86_22215 | Transcriptional regulator; Activator of copper-responsive regulon genes; Derived by automated computational analysis using gene prediction method: Protein Homology. | Multicopper oxidase; Laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.745 |
cueR | copA | SY86_08890 | SY86_23965 | Transcriptional regulator; Activator of copper-responsive regulon genes; Derived by automated computational analysis using gene prediction method: Protein Homology. | Copper-transporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.536 |
cueR | rpoD | SY86_08890 | SY86_21620 | Transcriptional regulator; Activator of copper-responsive regulon genes; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.967 |
cueR | topB | SY86_08890 | SY86_01955 | Transcriptional regulator; Activator of copper-responsive regulon genes; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | 0.613 |
cueR | uvrB | SY86_08890 | SY86_05955 | Transcriptional regulator; Activator of copper-responsive regulon genes; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.677 |
cueR | xerC | SY86_08890 | SY86_15495 | Transcriptional regulator; Activator of copper-responsive regulon genes; Derived by automated computational analysis using gene prediction method: Protein Homology. | Site-specific tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifical [...] | 0.613 |