STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEP73257.1Threonine synthase. (462 aa)    
Predicted Functional Partners:
SEQ90449.1
Homoserine dehydrogenase.
 
 0.983
SEQ17370.1
Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine.
  
 0.939
SEP71886.1
Threonine dehydratase.
  
 
 0.919
ilvA
L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 
 0.919
leuD
3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
  
 0.918
SEQ68987.1
L-threonine aldolase.
   
 0.891
SEP72790.1
Aspartate kinase; Belongs to the aspartokinase family.
  
 
 0.863
SEQ46019.1
Aspartate kinase.
  
 
 0.863
SEP73183.1
Ribosomal-protein-alanine N-acetyltransferase.
       0.856
SEP73221.1
Predicted Zn-dependent peptidase; Belongs to the peptidase M16 family.
       0.856
Your Current Organism:
Litorimicrobium taeanense
NCBI taxonomy Id: 657014
Other names: DSM 22007, KACC 13706, L. taeanense, Litorimicrobium taeanense Jin et al. 2011, Phaeobacter sp. G4, strain G4
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