KP79_PYT23559 protein (Mizuhopecten yessoensis)

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KP79_PYT23559

DNA replication ATP-dependent helicase/nuclease DNA2. (1783 aa)

Predicted Functional Partners:

KP79_PYT19025

0.988

KP79_PYT01817

0.984

FEN1

0.982

KP79_PYT09109

0.982

KP79_PYT15427

0.980

KP79_PYT07884

0.976

KP79_PYT05428

0.970

KP79_PYT09532

0.967

KP79_PYT11275

0.962

KP79_PYT15545

0.953

Your Current Organism:

Mizuhopecten yessoensis

NCBI taxonomy Id: 6573
Other names: M. yessoensis, Patinopecten yessoensis, Patiopecten yessoensis, Yesso scallop, ezo giant scallop

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FEN1	KP79_PYT01817	A0A210PFC9	A0A210Q4T9	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Exonuclease 1.	0.936
FEN1	KP79_PYT05428	A0A210PFC9	A0A210QGS1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.980
FEN1	KP79_PYT07884	A0A210PFC9	A0A210PMD2	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.936
FEN1	KP79_PYT09109	A0A210PFC9	A0A210PNJ6	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Replication protein A 32 kDa subunit.	0.848
FEN1	KP79_PYT09532	A0A210PFC9	A0A210QW28	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	WD repeat and HMG-box DNA-binding protein 1.	0.773
FEN1	KP79_PYT11275	A0A210PFC9	A0A210Q925	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA repair protein RAD52-like.	0.979
FEN1	KP79_PYT15427	A0A210PFC9	A0A210QB87	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family.	0.690
FEN1	KP79_PYT15545	A0A210PFC9	A0A210QGR4	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Tumor suppressor p53-binding protein 1.	0.859
FEN1	KP79_PYT19025	A0A210PFC9	A0A210PVJ8	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Werner syndrome ATP-dependent helicase-like.	0.987
FEN1	KP79_PYT23559	A0A210PFC9	A0A210PEQ2	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA replication ATP-dependent helicase/nuclease DNA2.	0.982
KP79_PYT01817	FEN1	A0A210Q4T9	A0A210PFC9	Exonuclease 1.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.936
KP79_PYT01817	KP79_PYT05428	A0A210Q4T9	A0A210QGS1	Exonuclease 1.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.983
KP79_PYT01817	KP79_PYT07884	A0A210Q4T9	A0A210PMD2	Exonuclease 1.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.901
KP79_PYT01817	KP79_PYT09109	A0A210Q4T9	A0A210PNJ6	Exonuclease 1.	Replication protein A 32 kDa subunit.	0.781
KP79_PYT01817	KP79_PYT09532	A0A210Q4T9	A0A210QW28	Exonuclease 1.	WD repeat and HMG-box DNA-binding protein 1.	0.811
KP79_PYT01817	KP79_PYT11275	A0A210Q4T9	A0A210Q925	Exonuclease 1.	DNA repair protein RAD52-like.	0.958
KP79_PYT01817	KP79_PYT15427	A0A210Q4T9	A0A210QB87	Exonuclease 1.	Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family.	0.961
KP79_PYT01817	KP79_PYT15545	A0A210Q4T9	A0A210QGR4	Exonuclease 1.	Tumor suppressor p53-binding protein 1.	0.943
KP79_PYT01817	KP79_PYT19025	A0A210Q4T9	A0A210PVJ8	Exonuclease 1.	Werner syndrome ATP-dependent helicase-like.	0.956
KP79_PYT01817	KP79_PYT23559	A0A210Q4T9	A0A210PEQ2	Exonuclease 1.	DNA replication ATP-dependent helicase/nuclease DNA2.	0.984