Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KP79_PYT22014Rho guanine nucleotide exchange factor 11. (1769 aa)    
Predicted Functional Partners:
KP79_PYT11479
Ras-like GTP-binding protein RHO.
   
 0.998
KP79_PYT05281
Guanine nucleotide-binding protein subunit alpha-13.
    
 0.994
KP79_PYT15079
Calcium and integrin-binding protein 1.
      
 0.796
KP79_PYT11498
Structural maintenance of chromosomes protein.
   
    0.786
KP79_PYT12956
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1.
   
 
 0.772
KP79_PYT20482
Protein ECT2.
     
 0.741
KP79_PYT07393
Rho GTPase-activating protein 20.
      
 0.721
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
      
 0.705
KP79_PYT20813
Rho guanine nucleotide exchange factor 7.
   
 0.700
KP79_PYT10714
Non-specific serine/threonine protein kinase.
   
 
 0.691
Your Current Organism:
Mizuhopecten yessoensis
NCBI taxonomy Id: 6573
Other names: M. yessoensis, Patinopecten yessoensis, Patiopecten yessoensis, Yesso scallop, ezo giant scallop
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