Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KP79_PYT03920SAGA-associated factor 11 homolog; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. (358 aa)    
Predicted Functional Partners:
KP79_PYT14090
Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...]
    
 0.995
KP79_PYT18400
Transcriptional adapter 3-B.
    
 0.994
KP79_PYT16429
SAGA-associated factor 29-like.
    
 0.992
KP79_PYT10018
Transcriptional adapter.
    
 0.991
KP79_PYT19465
Transformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family.
    
 0.991
KP79_PYT13217
Transcription factor SPT20-like.
    
 0.990
KP79_PYT12720
STAGA complex 65 subunit gamma.
    
 0.987
KP79_PYT07729
Transcription initiation protein SPT3-like.
    
 0.987
KP79_PYT06603
Transcription initiation factor TFIID subunit 12.
    
 0.987
KP79_PYT01897
Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.
    
 0.986
Your Current Organism:
Mizuhopecten yessoensis
NCBI taxonomy Id: 6573
Other names: M. yessoensis, Patinopecten yessoensis, Patiopecten yessoensis, Yesso scallop, ezo giant scallop
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.