Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KP79_PYT24397DNA primase; Belongs to the eukaryotic-type primase small subunit family. (417 aa)    
Predicted Functional Partners:
KP79_PYT08401
DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family.
  
 0.995
KP79_PYT24364
DNA primase large subunit.
  
 0.995
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 0.989
KP79_PYT21947
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
   
 0.989
KP79_PYT10551
DNA helicase; Belongs to the MCM family.
   
 0.988
KP79_PYT20615
Replication factor C subunit 4.
   
 0.984
KP79_PYT05855
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 
 0.982
KP79_PYT13455
DNA helicase; Belongs to the MCM family.
   
 0.980
KP79_PYT18438
DNA polymerase.
   
 0.978
KP79_PYT09913
DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.
   
 
 0.968
Your Current Organism:
Mizuhopecten yessoensis
NCBI taxonomy Id: 6573
Other names: M. yessoensis, Patinopecten yessoensis, Patiopecten yessoensis, Yesso scallop, ezo giant scallop
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