node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | KP79_PYT05292 | A0A210PFC9 | A0A210PSB1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Poly(ADP-ribose) glycohydrolase. | 0.548 |
FEN1 | KP79_PYT09920 | A0A210PFC9 | A0A210Q6T4 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Poly [ADP-ribose] polymerase. | 0.729 |
FEN1 | KP79_PYT11431 | A0A210PFC9 | A0A210PDW7 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA repair protein complementing XP-C cell. | 0.677 |
FEN1 | KP79_PYT14675 | A0A210PFC9 | A0A210R2J8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA repair protein complementing XP-A cell. | 0.784 |
FEN1 | KP79_PYT14893 | A0A210PFC9 | A0A210QDY6 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Breast cancer type 2 susceptibility protein-like. | 0.703 |
FEN1 | KP79_PYT15943 | A0A210PFC9 | A0A210PGK4 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA repair protein XRCC1. | 0.861 |
FEN1 | KP79_PYT17981 | A0A210PFC9 | A0A210PIP9 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Chromodomain-helicase-DNA-binding protein 1-like. | 0.452 |
FEN1 | KP79_PYT18046 | A0A210PFC9 | A0A210PZ73 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | X-ray repair cross-complementing protein 5. | 0.785 |
KP79_PYT05292 | FEN1 | A0A210PSB1 | A0A210PFC9 | Poly(ADP-ribose) glycohydrolase. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.548 |
KP79_PYT05292 | KP79_PYT09920 | A0A210PSB1 | A0A210Q6T4 | Poly(ADP-ribose) glycohydrolase. | Poly [ADP-ribose] polymerase. | 0.865 |
KP79_PYT05292 | KP79_PYT12498 | A0A210PSB1 | A0A210R1K2 | Poly(ADP-ribose) glycohydrolase. | UPF0609 protein C4orf27. | 0.529 |
KP79_PYT05292 | KP79_PYT15943 | A0A210PSB1 | A0A210PGK4 | Poly(ADP-ribose) glycohydrolase. | DNA repair protein XRCC1. | 0.564 |
KP79_PYT09920 | FEN1 | A0A210Q6T4 | A0A210PFC9 | Poly [ADP-ribose] polymerase. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.729 |
KP79_PYT09920 | KP79_PYT05292 | A0A210Q6T4 | A0A210PSB1 | Poly [ADP-ribose] polymerase. | Poly(ADP-ribose) glycohydrolase. | 0.865 |
KP79_PYT09920 | KP79_PYT11431 | A0A210Q6T4 | A0A210PDW7 | Poly [ADP-ribose] polymerase. | DNA repair protein complementing XP-C cell. | 0.753 |
KP79_PYT09920 | KP79_PYT12498 | A0A210Q6T4 | A0A210R1K2 | Poly [ADP-ribose] polymerase. | UPF0609 protein C4orf27. | 0.766 |
KP79_PYT09920 | KP79_PYT14675 | A0A210Q6T4 | A0A210R2J8 | Poly [ADP-ribose] polymerase. | DNA repair protein complementing XP-A cell. | 0.671 |
KP79_PYT09920 | KP79_PYT14893 | A0A210Q6T4 | A0A210QDY6 | Poly [ADP-ribose] polymerase. | Breast cancer type 2 susceptibility protein-like. | 0.666 |
KP79_PYT09920 | KP79_PYT15943 | A0A210Q6T4 | A0A210PGK4 | Poly [ADP-ribose] polymerase. | DNA repair protein XRCC1. | 0.663 |
KP79_PYT09920 | KP79_PYT17981 | A0A210Q6T4 | A0A210PIP9 | Poly [ADP-ribose] polymerase. | Chromodomain-helicase-DNA-binding protein 1-like. | 0.700 |