STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KP79_PYT23225Interferon-induced helicase C domain-containing protein 1. (900 aa)    
Predicted Functional Partners:
KP79_PYT07482
Uncharacterized protein.
    
 0.705
KP79_PYT10589
E3 ubiquitin-protein ligase FANCL.
    
 0.704
KP79_PYT12171
Uncharacterized protein.
    
 0.697
KP79_PYT13029
Uncharacterized protein.
   
 0.693
KP79_PYT08551
Uncharacterized protein.
    
 0.691
KP79_PYT25189
Fanconi anemia-associated protein of 24 kDa.
    
 0.639
KP79_PYT07884
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.610
KP79_PYT06236
Meiosis-specific with OB domain-containing protein.
    
 0.610
KP79_PYT05462
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
   
 
 0.569
KP79_PYT02001
Ubiquitin carboxyl-terminal hydrolase 25; Belongs to the peptidase C19 family.
   
 
 0.556
Your Current Organism:
Mizuhopecten yessoensis
NCBI taxonomy Id: 6573
Other names: M. yessoensis, Patinopecten yessoensis, Patiopecten yessoensis, Yesso scallop, ezo giant scallop
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