node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RBR_03840 | RBR_07640 | RBR_03840 | RBR_07640 | Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; Belongs to the TtcA family. | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.536 |
RBR_03840 | RBR_14670 | RBR_03840 | RBR_14670 | Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; Belongs to the TtcA family. | Ribosomal RNA small subunit methyltransferase RsmB. | 0.624 |
RBR_03840 | guaA | RBR_03840 | RBR_16990 | Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; Belongs to the TtcA family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.963 |
RBR_03840 | pheT | RBR_03840 | RBR_13120 | Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; Belongs to the TtcA family. | phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.699 |
RBR_03840 | polA | RBR_03840 | RBR_10600 | Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; Belongs to the TtcA family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.613 |
RBR_03840 | proS | RBR_03840 | RBR_08490 | Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; Belongs to the TtcA family. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). | 0.442 |
RBR_03840 | trmB | RBR_03840 | RBR_09670 | Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; Belongs to the TtcA family. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.642 |
RBR_03840 | truA | RBR_03840 | RBR_19020 | Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; Belongs to the TtcA family. | Pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.967 |
RBR_07630 | RBR_07640 | RBR_07630 | RBR_07640 | Hypothetical protein. | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.762 |
RBR_07630 | glyA | RBR_07630 | RBR_07650 | Hypothetical protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.586 |
RBR_07640 | RBR_03840 | RBR_07640 | RBR_03840 | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; Belongs to the TtcA family. | 0.536 |
RBR_07640 | RBR_07630 | RBR_07640 | RBR_07630 | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Hypothetical protein. | 0.762 |
RBR_07640 | RBR_14670 | RBR_07640 | RBR_14670 | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Ribosomal RNA small subunit methyltransferase RsmB. | 0.584 |
RBR_07640 | glyA | RBR_07640 | RBR_07650 | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.594 |
RBR_07640 | guaA | RBR_07640 | RBR_16990 | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.544 |
RBR_07640 | pheT | RBR_07640 | RBR_13120 | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.499 |
RBR_07640 | polA | RBR_07640 | RBR_10600 | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.612 |
RBR_07640 | proS | RBR_07640 | RBR_08490 | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). | 0.985 |
RBR_07640 | trmB | RBR_07640 | RBR_09670 | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.480 |
RBR_07640 | truA | RBR_07640 | RBR_19020 | tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.612 |