STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CIY_01870DnaJ domain. (158 aa)    
Predicted Functional Partners:
CIY_13990
Molecular chaperone.
  
 0.960
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.960
CIY_31230
Molecular chaperone, HSP90 family.
  
 0.935
CIY_31240
Molecular chaperone, HSP90 family.
  
 0.935
grpE
Molecular chaperone GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. [...]
  
 
 0.903
CIY_01100
Peptidyl-prolyl cis-trans isomerase (rotamase)-cyclophilin family; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 0.895
CIY_11130
Listeria-Bacteroides repeat domain (List_Bact_rpt).
  
 0.895
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 0.890
rpsB
SSU ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family.
   
 0.877
CIY_00840
ChAPs (Chs5p-Arf1p-binding proteins)./Tetratricopeptide repeat.
   
 0.874
Your Current Organism:
Butyrivibrio fibrisolvens 164
NCBI taxonomy Id: 657324
Other names: B. fibrisolvens 16/4, Butyrivibrio fibrisolvens 16/4, Butyrivibrio fibrisolvens str. 16/4, Butyrivibrio fibrisolvens strain 16/4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.