STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
polCDNA polymerase III catalytic subunit, PolC type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1480 aa)    
Predicted Functional Partners:
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 0.943
CIY_30580
DNA polymerase III, beta subunit.
    
 0.937
CIY_25050
DNA polymerase III catalytic subunit, DnaE type.
    
0.932
CIY_21630
DNA polymerase III, delta subunit.
    
 0.925
CIY_30210
DNA polymerase III, gamma/tau subunits.
  
 0.917
CIY_20740
Hypothetical protein.
       0.719
CIY_20730
Prephenate dehydratase.
     
 0.653
ispG
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
       0.651
tmcAL
Predicted nucleotidyltransferase; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
  
    0.645
CIY_20490
Uncharacterized protein conserved in bacteria; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
 
     0.644
Your Current Organism:
Butyrivibrio fibrisolvens 164
NCBI taxonomy Id: 657324
Other names: B. fibrisolvens 16/4, Butyrivibrio fibrisolvens 16/4, Butyrivibrio fibrisolvens str. 16/4, Butyrivibrio fibrisolvens strain 16/4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.