Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CIY_27770Isopropylmalate/homocitrate/citramalate synthases. (519 aa)    
Predicted Functional Partners:
CIY_16940
Isopropylmalate/homocitrate/citramalate synthases.
  
  
 
0.928
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
  
 
 0.740
CIY_27780
CMP-N-acetylneuraminic acid synthetase.
 
     0.693
CIY_09380
Branched chain amino acid aminotransferase apoenzyme.
  
 
 0.672
CIY_00410
Hypothetical protein.
  
     0.636
CIY_27790
Hypothetical protein.
       0.634
CIY_32950
GtrA-like protein.
  
     0.634
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
  
 0.612
leuC-2
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
  
 0.612
CIY_10260
Pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric.
  
  
 0.609
Your Current Organism:
Butyrivibrio fibrisolvens 164
NCBI taxonomy Id: 657324
Other names: B. fibrisolvens 16/4, Butyrivibrio fibrisolvens 16/4, Butyrivibrio fibrisolvens str. 16/4, Butyrivibrio fibrisolvens strain 16/4
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