node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEK89221.1 | SEK89256.1 | SAMN04488032_1085 | SAMN04488032_1086 | Hypoxia induced protein conserved region. | cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.861 |
SEK89221.1 | etfB | SAMN04488032_1085 | SAMN04488032_1087 | Hypoxia induced protein conserved region. | Electron transfer flavoprotein beta subunit. | 0.638 |
SEK89256.1 | SEK89221.1 | SAMN04488032_1086 | SAMN04488032_1085 | cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Hypoxia induced protein conserved region. | 0.861 |
SEK89256.1 | cobB_2 | SAMN04488032_1086 | SAMN04488032_10935 | cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.897 |
SEK89256.1 | cobD | SAMN04488032_1086 | SAMN04488032_10856 | cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | L-threonine O-3-phosphate decarboxylase. | 0.892 |
SEK89256.1 | cobD-2 | SAMN04488032_1086 | SAMN04488032_10857 | cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.897 |
SEK89256.1 | cobN | SAMN04488032_1086 | SAMN04488032_10865 | cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobaltochelatase CobN subunit. | 0.899 |
SEK89256.1 | cobO | SAMN04488032_1086 | SAMN04488032_10897 | cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.931 |
SEK89256.1 | cobP | SAMN04488032_1086 | SAMN04488032_10379 | cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.951 |
SEK89256.1 | cobQ | SAMN04488032_1086 | SAMN04488032_10511 | cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.946 |
SEK89256.1 | cobS_2 | SAMN04488032_1086 | SAMN04488032_104143 | cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.912 |
SEK89256.1 | etfB | SAMN04488032_1086 | SAMN04488032_1087 | cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Electron transfer flavoprotein beta subunit. | 0.678 |
cobB_2 | SEK89256.1 | SAMN04488032_10935 | SAMN04488032_1086 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.897 |
cobB_2 | cobD | SAMN04488032_10935 | SAMN04488032_10856 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | L-threonine O-3-phosphate decarboxylase. | 0.633 |
cobB_2 | cobD-2 | SAMN04488032_10935 | SAMN04488032_10857 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.911 |
cobB_2 | cobN | SAMN04488032_10935 | SAMN04488032_10865 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobaltochelatase CobN subunit. | 0.989 |
cobB_2 | cobO | SAMN04488032_10935 | SAMN04488032_10897 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.971 |
cobB_2 | cobP | SAMN04488032_10935 | SAMN04488032_10379 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Adenosylcobinamide kinase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.957 |
cobB_2 | cobQ | SAMN04488032_10935 | SAMN04488032_10511 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.986 |
cobB_2 | cobS_2 | SAMN04488032_10935 | SAMN04488032_104143 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.846 |