STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGN38611.1Hypothetical protein. (221 aa)    
Predicted Functional Partners:
EGN38610.1
Hypothetical protein.
       0.691
EGN43401.1
AraC family transcriptional regulator.
   
 
 0.625
EGN40374.1
DNA gyrase, B subunit.
   
 
 0.625
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.625
EGN42736.1
Diguanylate cyclase (GGDEF) domain-containing protein.
    
 0.568
EGN39426.1
Diguanylate cyclase (GGDEF) domain-containing protein.
    
 0.568
EGN32321.1
Diguanylate cyclase (GGDEF) domain-containing protein.
    
 0.568
EPC05072.1
Diguanylate cyclase (GGDEF) domain-containing protein.
    
 0.568
EGN40158.1
Hypothetical protein.
 
 
 
 0.505
EGN34133.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.494
Your Current Organism:
Lachnospiraceae bacterium 3157FAACT1
NCBI taxonomy Id: 658086
Other names: L. bacterium 3_1_57FAA_CT1, Lachnospiraceae bacterium 3_1_57FAA_CT1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.