node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EGN31476.1 | EGN34133.1 | HMPREF0994_05848 | HMPREF0994_04964 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.942 |
EGN31476.1 | EGN34437.1 | HMPREF0994_05848 | HMPREF0994_04810 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Hypothetical protein. | 0.853 |
EGN31476.1 | EGN41157.1 | HMPREF0994_05848 | HMPREF0994_02250 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | GMP synthase (glutamine-hydrolyzing) domain-containing protein. | 0.795 |
EGN31476.1 | EPC05203.1 | HMPREF0994_05848 | HMPREF0994_07150 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Hypothetical protein; Belongs to the 5'-nucleotidase family. | 0.417 |
EGN31476.1 | guaA | HMPREF0994_05848 | HMPREF0994_01855 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.795 |
EGN31476.1 | guaB | HMPREF0994_05848 | HMPREF0994_04535 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.579 |
EGN31476.1 | rplC | HMPREF0994_05848 | HMPREF0994_06379 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.537 |
EGN34133.1 | EGN31476.1 | HMPREF0994_04964 | HMPREF0994_05848 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.942 |
EGN34133.1 | EGN34437.1 | HMPREF0994_04964 | HMPREF0994_04810 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Hypothetical protein. | 0.850 |
EGN34133.1 | EGN41157.1 | HMPREF0994_04964 | HMPREF0994_02250 | Pyruvate kinase; Belongs to the pyruvate kinase family. | GMP synthase (glutamine-hydrolyzing) domain-containing protein. | 0.789 |
EGN34133.1 | guaA | HMPREF0994_04964 | HMPREF0994_01855 | Pyruvate kinase; Belongs to the pyruvate kinase family. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.789 |
EGN34133.1 | guaB | HMPREF0994_04964 | HMPREF0994_04535 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.861 |
EGN34133.1 | rplC | HMPREF0994_04964 | HMPREF0994_06379 | Pyruvate kinase; Belongs to the pyruvate kinase family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.983 |
EGN34133.1 | rplN | HMPREF0994_04964 | HMPREF0994_06368 | Pyruvate kinase; Belongs to the pyruvate kinase family. | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.983 |
EGN34133.1 | rpsK | HMPREF0994_04964 | HMPREF0994_06352 | Pyruvate kinase; Belongs to the pyruvate kinase family. | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.964 |
EGN34437.1 | EGN31476.1 | HMPREF0994_04810 | HMPREF0994_05848 | Hypothetical protein. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.853 |
EGN34437.1 | EGN34133.1 | HMPREF0994_04810 | HMPREF0994_04964 | Hypothetical protein. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.850 |
EGN34437.1 | EGN41157.1 | HMPREF0994_04810 | HMPREF0994_02250 | Hypothetical protein. | GMP synthase (glutamine-hydrolyzing) domain-containing protein. | 0.865 |
EGN34437.1 | EPC05203.1 | HMPREF0994_04810 | HMPREF0994_07150 | Hypothetical protein. | Hypothetical protein; Belongs to the 5'-nucleotidase family. | 0.927 |
EGN34437.1 | guaA | HMPREF0994_04810 | HMPREF0994_01855 | Hypothetical protein. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.865 |