STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGN32868.13-oxoacyl-[acyl-carrier protein] reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (239 aa)    
Predicted Functional Partners:
EGN34120.1
Beta-ketoacyl-acyl-carrier-protein synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 0.981
EGN34122.1
Malonyl CoA-acyl carrier protein transacylase.
 0.978
fabZ
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
 
 0.974
fabH
3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.966
EGN43485.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase.
   
 0.964
EGN48032.1
Amino acid adenylation domain-containing protein; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.930
EGN46642.1
PTS system, glucose subfamily, IIA component.
     
 0.847
EGN42708.1
1-phosphofructokinase family hexose kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
   
 
 0.802
EGN34121.1
3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 
0.796
EGN34133.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.732
Your Current Organism:
Lachnospiraceae bacterium 3157FAACT1
NCBI taxonomy Id: 658086
Other names: L. bacterium 3_1_57FAA_CT1, Lachnospiraceae bacterium 3_1_57FAA_CT1
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