node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHH13214.1 | SHH68063.1 | SAMN04488135_102272 | SAMN04488135_104163 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.562 |
SHH13214.1 | SHI19486.1 | SAMN04488135_102272 | SAMN04488135_112118 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | Lipoate-protein ligase A. | 0.912 |
SHH13214.1 | SHI21752.1 | SAMN04488135_102272 | SAMN04488135_113152 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | Dihydrolipoamide dehydrogenase. | 0.964 |
SHH13214.1 | SHI28826.1 | SAMN04488135_102272 | SAMN04488135_12026 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | 0.411 |
SHH13214.1 | gcvH | SAMN04488135_102272 | SAMN04488135_10285 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.869 |
SHH13214.1 | gcvP | SAMN04488135_102272 | SAMN04488135_10284 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.841 |
SHH13214.1 | lipA | SAMN04488135_102272 | SAMN04488135_103242 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.623 |
SHH13214.1 | lipB | SAMN04488135_102272 | SAMN04488135_103240 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | Lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.546 |
SHH44328.1 | lipA | SAMN04488135_103239 | SAMN04488135_103242 | Hypothetical protein; Belongs to the UPF0250 family. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.637 |
SHH44328.1 | lipB | SAMN04488135_103239 | SAMN04488135_103240 | Hypothetical protein; Belongs to the UPF0250 family. | Lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.921 |
SHH54464.1 | lipA | SAMN04488135_103486 | SAMN04488135_103242 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.621 |
SHH68063.1 | SHH13214.1 | SAMN04488135_104163 | SAMN04488135_102272 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | 0.562 |
SHH68063.1 | SHI19486.1 | SAMN04488135_104163 | SAMN04488135_112118 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Lipoate-protein ligase A. | 0.912 |
SHH68063.1 | SHI21752.1 | SAMN04488135_104163 | SAMN04488135_113152 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoamide dehydrogenase. | 0.984 |
SHH68063.1 | SHI28826.1 | SAMN04488135_104163 | SAMN04488135_12026 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | 0.426 |
SHH68063.1 | gcvH | SAMN04488135_104163 | SAMN04488135_10285 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.869 |
SHH68063.1 | gcvP | SAMN04488135_104163 | SAMN04488135_10284 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.841 |
SHH68063.1 | lipA | SAMN04488135_104163 | SAMN04488135_103242 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.618 |
SHH68063.1 | lipB | SAMN04488135_104163 | SAMN04488135_103240 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.525 |
SHI19486.1 | SHH13214.1 | SAMN04488135_112118 | SAMN04488135_102272 | Lipoate-protein ligase A. | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | 0.912 |