node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHH23532.1 | SHH23574.1 | SAMN04488135_102524 | SAMN04488135_102525 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | 0.999 |
SHH23532.1 | SHH43976.1 | SAMN04488135_102524 | SAMN04488135_103231 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.922 |
SHH23532.1 | gmhA | SAMN04488135_102524 | SAMN04488135_102536 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | D-sedoheptulose 7-phosphate isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | 0.750 |
SHH23532.1 | kdsA | SAMN04488135_102524 | SAMN04488135_104344 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); Belongs to the KdsA family. | 0.993 |
SHH23532.1 | kdsB | SAMN04488135_102524 | SAMN04488135_107152 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase); Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.951 |
SHH23532.1 | lpxA | SAMN04488135_102524 | SAMN04488135_105272 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.942 |
SHH23532.1 | lpxB | SAMN04488135_102524 | SAMN04488135_105271 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.949 |
SHH23532.1 | lpxC | SAMN04488135_102524 | SAMN04488135_12622 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.946 |
SHH23532.1 | lpxD | SAMN04488135_102524 | SAMN04488135_105274 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.948 |
SHH23532.1 | lpxK | SAMN04488135_102524 | SAMN04488135_107154 | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.950 |
SHH23574.1 | SHH23532.1 | SAMN04488135_102525 | SAMN04488135_102524 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.999 |
SHH23574.1 | SHH43976.1 | SAMN04488135_102525 | SAMN04488135_103231 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.883 |
SHH23574.1 | gmhA | SAMN04488135_102525 | SAMN04488135_102536 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | D-sedoheptulose 7-phosphate isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate. | 0.704 |
SHH23574.1 | kdsA | SAMN04488135_102525 | SAMN04488135_104344 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); Belongs to the KdsA family. | 0.995 |
SHH23574.1 | kdsB | SAMN04488135_102525 | SAMN04488135_107152 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase); Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.983 |
SHH23574.1 | lpxA | SAMN04488135_102525 | SAMN04488135_105272 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.850 |
SHH23574.1 | lpxB | SAMN04488135_102525 | SAMN04488135_105271 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.855 |
SHH23574.1 | lpxC | SAMN04488135_102525 | SAMN04488135_12622 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.865 |
SHH23574.1 | lpxD | SAMN04488135_102525 | SAMN04488135_105274 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.856 |
SHH23574.1 | lpxK | SAMN04488135_102525 | SAMN04488135_107154 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase). | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.843 |