| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CKC_01750 | mscL | CKC_01750 | CKC_00560 | COG0670 Integral membrane protein, interacts with FtsH; Belongs to the BI1 family. | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.521 |
| CKC_01905 | CKC_05460 | CKC_01905 | CKC_05460 | COG0192 S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI). | 0.487 |
| CKC_01905 | mscL | CKC_01905 | CKC_00560 | COG0192 S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.762 |
| CKC_01905 | polA | CKC_01905 | CKC_05465 | COG0192 S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.487 |
| CKC_01905 | ribH | CKC_01905 | CKC_02410 | COG0192 S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | Riboflavin synthase subunit beta; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.934 |
| CKC_04510 | mscL | CKC_04510 | CKC_00560 | Potassium-efflux system protein; COG4651 Kef-type K+ transport system, predicted NAD-binding component; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.509 |
| CKC_04510 | secF | CKC_04510 | CKC_04505 | Potassium-efflux system protein; COG4651 Kef-type K+ transport system, predicted NAD-binding component; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | Bifunctional preprotein translocase subunit SecD/SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.685 |
| CKC_04545 | mscL | CKC_04545 | CKC_00560 | ABC transporter, nucleotide binding/ATPase protein; COG1132 ABC-type multidrug transport system, ATPase and permease components. | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.414 |
| CKC_04950 | mscL | CKC_04950 | CKC_00560 | COG0281 Malic enzyme. | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.443 |
| CKC_04950 | secF | CKC_04950 | CKC_04505 | COG0281 Malic enzyme. | Bifunctional preprotein translocase subunit SecD/SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.430 |
| CKC_05090 | mscL | CKC_05090 | CKC_00560 | Lipid A ABC exporter family, fused ATPase and inner membrane subunits; COG1132 ABC-type multidrug transport system, ATPase and permease components. | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.414 |
| CKC_05460 | CKC_01905 | CKC_05460 | CKC_01905 | DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI). | COG0192 S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | 0.487 |
| CKC_05460 | mscL | CKC_05460 | CKC_00560 | DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI). | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.489 |
| CKC_05460 | polA | CKC_05460 | CKC_05465 | DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI). | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.998 |
| CKC_05460 | secF | CKC_05460 | CKC_04505 | DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI). | Bifunctional preprotein translocase subunit SecD/SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.711 |
| mscL | CKC_01750 | CKC_00560 | CKC_01750 | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | COG0670 Integral membrane protein, interacts with FtsH; Belongs to the BI1 family. | 0.521 |
| mscL | CKC_01905 | CKC_00560 | CKC_01905 | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | COG0192 S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | 0.762 |
| mscL | CKC_04510 | CKC_00560 | CKC_04510 | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | Potassium-efflux system protein; COG4651 Kef-type K+ transport system, predicted NAD-binding component; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. | 0.509 |
| mscL | CKC_04545 | CKC_00560 | CKC_04545 | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | ABC transporter, nucleotide binding/ATPase protein; COG1132 ABC-type multidrug transport system, ATPase and permease components. | 0.414 |
| mscL | CKC_04950 | CKC_00560 | CKC_04950 | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | COG0281 Malic enzyme. | 0.443 |