STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKC_01100COG0272 NAD-dependent DNA ligase (contains BRCT domain type II). (127 aa)    
Predicted Functional Partners:
CKC_01105
COG0194 Guanylate kinase.
       0.774
CKC_01080
Hypothetical protein.
       0.773
CKC_01085
Putative DNA polymerase from bacteriophage origin; COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains.
       0.773
CKC_01090
VRR-NUC domain-containing protein.
       0.773
CKC_01095
SNF2 related protein; COG0553 Superfamily II DNA/RNA helicases, SNF2 family.
       0.773
CKC_01110
Hypothetical protein.
       0.741
CKC_01115
Hypothetical protein.
       0.741
CKC_01075
COG3617 Prophage antirepressor.
       0.732
CKC_01070
Anti-repressor protein; COG3646 Uncharacterized phage-encoded protein.
       0.621
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
    
 
 0.595
Your Current Organism:
Liberibacter solanacearum
NCBI taxonomy Id: 658172
Other names: C. Liberibacter solanacearum CLso-ZC1, Candidatus Liberibacter solanacearum CLso-ZC1, Candidatus Liberibacter solanacearum str. CLso-ZC1, Candidatus Liberibacter solanacearum strain CLso-ZC1
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