node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CKC_01160 | CKC_01180 | CKC_01160 | CKC_01180 | 3-deoxy-manno-octulosonate cytidylyltransferase; COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase; Belongs to the KdsB family. | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.578 |
CKC_01160 | CKC_02180 | CKC_01160 | CKC_02180 | 3-deoxy-manno-octulosonate cytidylyltransferase; COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase; Belongs to the KdsB family. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.976 |
CKC_01160 | lpxB | CKC_01160 | CKC_01170 | 3-deoxy-manno-octulosonate cytidylyltransferase; COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase; Belongs to the KdsB family. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.660 |
CKC_01160 | lpxC | CKC_01160 | CKC_04110 | 3-deoxy-manno-octulosonate cytidylyltransferase; COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase; Belongs to the KdsB family. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.581 |
CKC_01160 | lpxD | CKC_01160 | CKC_01190 | 3-deoxy-manno-octulosonate cytidylyltransferase; COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase; Belongs to the KdsB family. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.567 |
CKC_01160 | lpxK | CKC_01160 | CKC_02185 | 3-deoxy-manno-octulosonate cytidylyltransferase; COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase; Belongs to the KdsB family. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.664 |
CKC_01175 | CKC_01180 | CKC_01175 | CKC_01180 | COG3494 Uncharacterized protein conserved in bacteria. | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.914 |
CKC_01175 | CKC_01195 | CKC_01175 | CKC_01195 | COG3494 Uncharacterized protein conserved in bacteria. | Surface antigen (D15); COG4775 Outer membrane protein/protective antigen OMA87. | 0.661 |
CKC_01175 | CKC_02180 | CKC_01175 | CKC_02180 | COG3494 Uncharacterized protein conserved in bacteria. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.682 |
CKC_01175 | fabZ | CKC_01175 | CKC_01185 | COG3494 Uncharacterized protein conserved in bacteria. | (3R)-hydroxymyristoyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.759 |
CKC_01175 | lpxB | CKC_01175 | CKC_01170 | COG3494 Uncharacterized protein conserved in bacteria. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.965 |
CKC_01175 | lpxC | CKC_01175 | CKC_04110 | COG3494 Uncharacterized protein conserved in bacteria. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.556 |
CKC_01175 | lpxD | CKC_01175 | CKC_01190 | COG3494 Uncharacterized protein conserved in bacteria. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.887 |
CKC_01175 | lpxK | CKC_01175 | CKC_02185 | COG3494 Uncharacterized protein conserved in bacteria. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.677 |
CKC_01180 | CKC_01160 | CKC_01180 | CKC_01160 | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 3-deoxy-manno-octulosonate cytidylyltransferase; COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase; Belongs to the KdsB family. | 0.578 |
CKC_01180 | CKC_01175 | CKC_01180 | CKC_01175 | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | COG3494 Uncharacterized protein conserved in bacteria. | 0.914 |
CKC_01180 | CKC_01195 | CKC_01180 | CKC_01195 | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Surface antigen (D15); COG4775 Outer membrane protein/protective antigen OMA87. | 0.842 |
CKC_01180 | CKC_02180 | CKC_01180 | CKC_02180 | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.806 |
CKC_01180 | fabZ | CKC_01180 | CKC_01185 | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | (3R)-hydroxymyristoyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.979 |
CKC_01180 | lpxB | CKC_01180 | CKC_01170 | UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.991 |