| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CKC_01430 | CKC_04950 | CKC_01430 | CKC_04950 | Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | COG0281 Malic enzyme. | 0.446 |
| CKC_01430 | cmk | CKC_01430 | CKC_01725 | Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | COG0283 Cytidylate kinase. | 0.908 |
| CKC_01430 | ndk | CKC_01430 | CKC_02240 | Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.908 |
| CKC_01430 | pyrF | CKC_01430 | CKC_01745 | Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.900 |
| CKC_01430 | pyrG | CKC_01430 | CKC_04370 | Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.908 |
| CKC_01430 | pyrH | CKC_01430 | CKC_01220 | Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.900 |
| CKC_01430 | radC | CKC_01430 | CKC_04675 | Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | COG2003 DNA repair proteins; Belongs to the UPF0758 family. | 0.852 |
| CKC_01430 | surE | CKC_01430 | CKC_02290 | Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
| CKC_01430 | thyA | CKC_01430 | CKC_03770 | Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.900 |
| CKC_01430 | tmk | CKC_01430 | CKC_02955 | Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.908 |
| CKC_04950 | CKC_01430 | CKC_04950 | CKC_01430 | COG0281 Malic enzyme. | Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.446 |
| CKC_04950 | ndk | CKC_04950 | CKC_02240 | COG0281 Malic enzyme. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.432 |
| CKC_04950 | pyrF | CKC_04950 | CKC_01745 | COG0281 Malic enzyme. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.546 |
| CKC_04950 | pyrG | CKC_04950 | CKC_04370 | COG0281 Malic enzyme. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.510 |
| CKC_04950 | pyrH | CKC_04950 | CKC_01220 | COG0281 Malic enzyme. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.483 |
| cmk | CKC_01430 | CKC_01725 | CKC_01430 | COG0283 Cytidylate kinase. | Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.908 |
| cmk | ndk | CKC_01725 | CKC_02240 | COG0283 Cytidylate kinase. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.944 |
| cmk | pyrF | CKC_01725 | CKC_01745 | COG0283 Cytidylate kinase. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.647 |
| cmk | pyrG | CKC_01725 | CKC_04370 | COG0283 Cytidylate kinase. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.501 |
| cmk | pyrH | CKC_01725 | CKC_01220 | COG0283 Cytidylate kinase. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.509 |