Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CKC_01445COG4395 Uncharacterized protein conserved in bacteria. (231 aa)    
Predicted Functional Partners:
CKC_01360
Putative cytoplasmic protein; COG3820 Uncharacterized protein conserved in bacteria.
  
     0.727
CKC_01485
Double-strand break repair protein AddB; COG3893 Inactivated superfamily I helicase.
  
     0.715
CKC_03125
HemY domain-containing protein; COG0457 FOG: TPR repeat.
  
     0.656
CKC_03430
COG0711 F0F1-type ATP synthase, subunit b; Belongs to the ATPase B chain family.
  
     0.651
CKC_01480
Double-strand break repair helicase AddA; COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); Belongs to the helicase family. UvrD subfamily.
  
     0.640
CKC_03565
COG3750 Uncharacterized protein conserved in bacteria; Belongs to the UPF0335 family.
  
     0.589
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.580
CKC_04645
Putative oxidoreductase protein.
  
     0.575
CKC_02120
COG1495 Disulfide bond formation protein DsbB.
  
     0.556
CKC_00055
Hypothetical protein; COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family.
  
     0.535
Your Current Organism:
Liberibacter solanacearum
NCBI taxonomy Id: 658172
Other names: C. Liberibacter solanacearum CLso-ZC1, Candidatus Liberibacter solanacearum CLso-ZC1, Candidatus Liberibacter solanacearum str. CLso-ZC1, Candidatus Liberibacter solanacearum strain CLso-ZC1
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