| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CKC_02150 | CKC_02160 | CKC_02150 | CKC_02160 | GTP cyclohydrolase II protein (riboflavin biosynthesis); Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | Putative ribosomal large subunit pseudouridine synthase B; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. | 0.530 |
| CKC_02150 | CKC_02165 | CKC_02150 | CKC_02165 | GTP cyclohydrolase II protein (riboflavin biosynthesis); Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | Hypothetical protein; COG0742 N6-adenine-specific methylase. | 0.542 |
| CKC_02150 | CKC_02400 | CKC_02150 | CKC_02400 | GTP cyclohydrolase II protein (riboflavin biosynthesis); Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | 5-amino-6-(5-phosphoribosylamino)uracil reductase/diaminohydroxyphosphoribosylaminopyrimidine; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
| CKC_02150 | CKC_04815 | CKC_02150 | CKC_04815 | GTP cyclohydrolase II protein (riboflavin biosynthesis); Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | birA bifunctional protein; COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | 0.625 |
| CKC_02150 | guaA | CKC_02150 | CKC_01960 | GTP cyclohydrolase II protein (riboflavin biosynthesis); Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.769 |
| CKC_02150 | guaB | CKC_02150 | CKC_04730 | GTP cyclohydrolase II protein (riboflavin biosynthesis); Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.858 |
| CKC_02150 | tadA | CKC_02150 | CKC_02155 | GTP cyclohydrolase II protein (riboflavin biosynthesis); Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | Cytidine/deoxycytidylate deaminase, zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.800 |
| CKC_02160 | CKC_02150 | CKC_02160 | CKC_02150 | Putative ribosomal large subunit pseudouridine synthase B; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. | GTP cyclohydrolase II protein (riboflavin biosynthesis); Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | 0.530 |
| CKC_02160 | CKC_02165 | CKC_02160 | CKC_02165 | Putative ribosomal large subunit pseudouridine synthase B; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. | Hypothetical protein; COG0742 N6-adenine-specific methylase. | 0.826 |
| CKC_02160 | CKC_05520 | CKC_02160 | CKC_05520 | Putative ribosomal large subunit pseudouridine synthase B; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. | Exodeoxyribonuclease III protein; COG0708 Exonuclease III. | 0.834 |
| CKC_02160 | tadA | CKC_02160 | CKC_02155 | Putative ribosomal large subunit pseudouridine synthase B; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. | Cytidine/deoxycytidylate deaminase, zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.577 |
| CKC_02165 | CKC_02150 | CKC_02165 | CKC_02150 | Hypothetical protein; COG0742 N6-adenine-specific methylase. | GTP cyclohydrolase II protein (riboflavin biosynthesis); Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | 0.542 |
| CKC_02165 | CKC_02160 | CKC_02165 | CKC_02160 | Hypothetical protein; COG0742 N6-adenine-specific methylase. | Putative ribosomal large subunit pseudouridine synthase B; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. | 0.826 |
| CKC_02165 | tadA | CKC_02165 | CKC_02155 | Hypothetical protein; COG0742 N6-adenine-specific methylase. | Cytidine/deoxycytidylate deaminase, zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.579 |
| CKC_02400 | CKC_02150 | CKC_02400 | CKC_02150 | 5-amino-6-(5-phosphoribosylamino)uracil reductase/diaminohydroxyphosphoribosylaminopyrimidine; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase II protein (riboflavin biosynthesis); Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | 0.999 |
| CKC_02400 | CKC_04815 | CKC_02400 | CKC_04815 | 5-amino-6-(5-phosphoribosylamino)uracil reductase/diaminohydroxyphosphoribosylaminopyrimidine; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | birA bifunctional protein; COG0340 Biotin-(acetyl-CoA carboxylase) ligase. | 0.628 |
| CKC_02400 | CKC_05460 | CKC_02400 | CKC_05460 | 5-amino-6-(5-phosphoribosylamino)uracil reductase/diaminohydroxyphosphoribosylaminopyrimidine; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | DNA polymerase I; COG0258 5'-3' exonuclease (including N-terminal domain of PolI). | 0.617 |
| CKC_02400 | guaA | CKC_02400 | CKC_01960 | 5-amino-6-(5-phosphoribosylamino)uracil reductase/diaminohydroxyphosphoribosylaminopyrimidine; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.712 |
| CKC_02400 | guaB | CKC_02400 | CKC_04730 | 5-amino-6-(5-phosphoribosylamino)uracil reductase/diaminohydroxyphosphoribosylaminopyrimidine; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.709 |
| CKC_02400 | polA | CKC_02400 | CKC_05465 | 5-amino-6-(5-phosphoribosylamino)uracil reductase/diaminohydroxyphosphoribosylaminopyrimidine; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.617 |