| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CKC_00840 | CKC_04285 | CKC_00840 | CKC_04285 | Octaprenyl-diphosphate synthase protein; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | 0.654 |
| CKC_00840 | ubiA | CKC_00840 | CKC_04410 | Octaprenyl-diphosphate synthase protein; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | Prenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.912 |
| CKC_00840 | ubiE | CKC_00840 | CKC_00375 | Octaprenyl-diphosphate synthase protein; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.494 |
| CKC_01130 | CKC_04285 | CKC_01130 | CKC_04285 | Probable FAD-dependent oxidoreductase protein; COG0277 FAD/FMN-containing dehydrogenases. | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | 0.515 |
| CKC_01130 | atpD | CKC_01130 | CKC_00325 | Probable FAD-dependent oxidoreductase protein; COG0277 FAD/FMN-containing dehydrogenases. | F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. | 0.636 |
| CKC_01130 | ubiA | CKC_01130 | CKC_04410 | Probable FAD-dependent oxidoreductase protein; COG0277 FAD/FMN-containing dehydrogenases. | Prenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.704 |
| CKC_02150 | CKC_02400 | CKC_02150 | CKC_02400 | GTP cyclohydrolase II protein (riboflavin biosynthesis); Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | 5-amino-6-(5-phosphoribosylamino)uracil reductase/diaminohydroxyphosphoribosylaminopyrimidine; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
| CKC_02150 | ubiA | CKC_02150 | CKC_04410 | GTP cyclohydrolase II protein (riboflavin biosynthesis); Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | Prenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.588 |
| CKC_02150 | ubiE | CKC_02150 | CKC_00375 | GTP cyclohydrolase II protein (riboflavin biosynthesis); Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.463 |
| CKC_02310 | CKC_04925 | CKC_02310 | CKC_04925 | Hypothetical protein; COG2867 Oligoketide cyclase/lipid transport protein. | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.469 |
| CKC_02310 | ubiA | CKC_02310 | CKC_04410 | Hypothetical protein; COG2867 Oligoketide cyclase/lipid transport protein. | Prenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.585 |
| CKC_02310 | ubiG | CKC_02310 | CKC_04790 | Hypothetical protein; COG2867 Oligoketide cyclase/lipid transport protein. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.623 |
| CKC_02400 | CKC_02150 | CKC_02400 | CKC_02150 | 5-amino-6-(5-phosphoribosylamino)uracil reductase/diaminohydroxyphosphoribosylaminopyrimidine; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase II protein (riboflavin biosynthesis); Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. Belongs to the DHBP synthase family. | 0.999 |
| CKC_02400 | CKC_04925 | CKC_02400 | CKC_04925 | 5-amino-6-(5-phosphoribosylamino)uracil reductase/diaminohydroxyphosphoribosylaminopyrimidine; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.609 |
| CKC_02400 | ubiA | CKC_02400 | CKC_04410 | 5-amino-6-(5-phosphoribosylamino)uracil reductase/diaminohydroxyphosphoribosylaminopyrimidine; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Prenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.614 |
| CKC_02400 | ubiE | CKC_02400 | CKC_00375 | 5-amino-6-(5-phosphoribosylamino)uracil reductase/diaminohydroxyphosphoribosylaminopyrimidine; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.500 |
| CKC_02400 | ubiG | CKC_02400 | CKC_04790 | 5-amino-6-(5-phosphoribosylamino)uracil reductase/diaminohydroxyphosphoribosylaminopyrimidine; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.581 |
| CKC_04285 | CKC_00840 | CKC_04285 | CKC_00840 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | Octaprenyl-diphosphate synthase protein; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.654 |
| CKC_04285 | CKC_01130 | CKC_04285 | CKC_01130 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | Probable FAD-dependent oxidoreductase protein; COG0277 FAD/FMN-containing dehydrogenases. | 0.515 |
| CKC_04285 | CKC_04925 | CKC_04285 | CKC_04925 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.474 |