STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LDG_5154Hypothetical protein; Belongs to the small heat shock protein (HSP20) family. (146 aa)    
Predicted Functional Partners:
LDG_6135
Hypothetical protein.
 
 
 0.754
LDG_5315
ATP binding protease component ClpA; Belongs to the ClpA/ClpB family.
  
 
 0.717
LDG_8910
Chaperone protein ClpB.
  
 
 0.717
LDG_8911
Endopeptidase Clp ATP-binding chain B (ClpB); Belongs to the ClpA/ClpB family.
  
 
 0.717
LDG_5155
Hypothetical protein.
       0.682
dnaK
Chaperone protein DnaK (heat shock 70 kDa protein,HSP70); Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.640
grpE
Heat-shock protein GrpE(HSP-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Sever [...]
  
 
 0.522
htpG
Heat shock protein 90; Molecular chaperone. Has ATPase activity.
  
  
 0.521
LDG_5722
Glutamine synthetase, type I.
    
   0.482
LDG_8054
Hypothetical protein; Belongs to the glutamine synthetase family.
    
   0.482
Your Current Organism:
Legionella drancourtii
NCBI taxonomy Id: 658187
Other names: L. drancourtii LLAP12, Legionella drancourtii LLAP12, Legionella drancourtii str. LLAP12, Legionella drancourtii strain LLAP12
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.