STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LDG_5267Hypothetical protein; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa)    
Predicted Functional Partners:
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.956
LDG_5863
Cystathionine beta-lyase.
     
 0.871
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
   
 
 0.870
LDG_5912
Hypothetical protein.
     
  0.844
LDG_8562
CDP-diacylglycerol-serine-O- phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
  0.844
trpB
Hypothetical protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
  0.844
gcvT
Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.750
LDG_5269
Hypothetical protein.
    
  0.736
LDG_5633
Hypothetical protein; In the C-terminal section; belongs to the homoserine dehydrogenase family.
  
 
 0.722
LDG_5268
Macrophage infectivity potentiator.
       0.720
Your Current Organism:
Legionella drancourtii
NCBI taxonomy Id: 658187
Other names: L. drancourtii LLAP12, Legionella drancourtii LLAP12, Legionella drancourtii str. LLAP12, Legionella drancourtii strain LLAP12
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.