STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
msrABifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (289 aa)    
Predicted Functional Partners:
LDG_6754
Hypothetical protein.
 
 
 
 0.981
LDG_7337
Hypothetical protein.
   
 0.971
LDG_5481
Hypothetical protein.
   
 0.939
LDG_6527
Hypothetical protein.
   
 0.939
LDG_7161
Hypothetical protein; Belongs to the glutathione peroxidase family.
  
 
 0.871
LDG_6666
Hypothetical protein; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
  
 
 0.867
LDG_7512
Hypothetical protein.
  
 
 0.867
LDG_5406
Hypothetical protein.
       0.839
grpE
Heat-shock protein GrpE(HSP-70 cofactor); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Sever [...]
   
 
 0.821
LDG_8893
Thioredoxin reductase.
  
  
 0.765
Your Current Organism:
Legionella drancourtii
NCBI taxonomy Id: 658187
Other names: L. drancourtii LLAP12, Legionella drancourtii LLAP12, Legionella drancourtii str. LLAP12, Legionella drancourtii strain LLAP12
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.