STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LDG_5434Thiamine pyrophosphate protein domain protein TPP-binding; Belongs to the TPP enzyme family. (575 aa)    
Predicted Functional Partners:
LDG_8197
DlpA protein (isocitrate and isopropylmalate dehydrogenase family protein).
  
 0.808
LDG_7358
Malate oxidoreductase.
   
 0.788
LDG_7574
Hypothetical protein.
   
 0.788
LDG_8827
Hypothetical protein.
   
 0.788
LDG_8802
Hypothetical protein.
  
 
 0.774
LDG_6049
Pyruvate kinase II; Belongs to the pyruvate kinase family.
  
 0.756
LDG_6202
Hypothetical protein; Belongs to the aldehyde dehydrogenase family.
    
 0.753
LDG_6057
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
     
 0.744
LDG_9077
Hypothetical protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.739
LDG_8195
Hypothetical protein.
  
 
 0.730
Your Current Organism:
Legionella drancourtii
NCBI taxonomy Id: 658187
Other names: L. drancourtii LLAP12, Legionella drancourtii LLAP12, Legionella drancourtii str. LLAP12, Legionella drancourtii strain LLAP12
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.