| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LDG_5312 | LDG_6057 | LDG_5312 | LDG_6057 | Hypothetical protein. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.602 |
| LDG_5312 | LDG_6846 | LDG_5312 | LDG_6846 | Hypothetical protein. | Hypothetical protein; Belongs to the citrate synthase family. | 0.916 |
| LDG_5312 | LDG_7053 | LDG_5312 | LDG_7053 | Hypothetical protein. | Hypothetical protein. | 0.722 |
| LDG_5312 | LDG_7213 | LDG_5312 | LDG_7213 | Hypothetical protein. | Hypothetical protein. | 0.975 |
| LDG_5312 | LDG_8157 | LDG_5312 | LDG_8157 | Hypothetical protein. | Succinate dehydrogenase iron-sulfur subunit. | 0.891 |
| LDG_5312 | LDG_8158 | LDG_5312 | LDG_8158 | Hypothetical protein. | Succinate dehydrogenase flavoprotein subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.917 |
| LDG_5312 | LDG_9011 | LDG_5312 | LDG_9011 | Hypothetical protein. | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.982 |
| LDG_5312 | mdh | LDG_5312 | LDG_6618 | Hypothetical protein. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.974 |
| LDG_5312 | sucC | LDG_5312 | LDG_8154 | Hypothetical protein. | Succinyl CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.923 |
| LDG_6057 | LDG_5312 | LDG_6057 | LDG_5312 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Hypothetical protein. | 0.602 |
| LDG_6057 | LDG_6846 | LDG_6057 | LDG_6846 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Hypothetical protein; Belongs to the citrate synthase family. | 0.922 |
| LDG_6057 | LDG_7053 | LDG_6057 | LDG_7053 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Hypothetical protein. | 0.904 |
| LDG_6057 | LDG_8157 | LDG_6057 | LDG_8157 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Succinate dehydrogenase iron-sulfur subunit. | 0.704 |
| LDG_6057 | LDG_8158 | LDG_6057 | LDG_8158 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Succinate dehydrogenase flavoprotein subunit A; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.595 |
| LDG_6057 | mdh | LDG_6057 | LDG_6618 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.440 |
| LDG_6057 | prpB | LDG_6057 | LDG_7927 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Putative carboxyphosphonoenolpyruvate phosphonomutase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 0.821 |
| LDG_6057 | sucC | LDG_6057 | LDG_8154 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Succinyl CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.741 |
| LDG_6846 | LDG_5312 | LDG_6846 | LDG_5312 | Hypothetical protein; Belongs to the citrate synthase family. | Hypothetical protein. | 0.916 |
| LDG_6846 | LDG_6057 | LDG_6846 | LDG_6057 | Hypothetical protein; Belongs to the citrate synthase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.922 |
| LDG_6846 | LDG_7053 | LDG_6846 | LDG_7053 | Hypothetical protein; Belongs to the citrate synthase family. | Hypothetical protein. | 0.899 |
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