clpP protein (Legionella drancourtii) - STRING interaction network

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clpP

ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (213 aa)

Predicted Functional Partners:

clpX

0.999

LDG_7719

0.995

LDG_8910

0.974

LDG_6135

0.973

LDG_5315

0.969

LDG_8911

0.969

clpS

0.897

dnaK

0.888

groS

0.888

tig

0.878

Your Current Organism:

Legionella drancourtii

NCBI taxonomy Id: 658187
Other names: L. drancourtii LLAP12, Legionella drancourtii LLAP12, Legionella drancourtii str. LLAP12, Legionella drancourtii strain LLAP12

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LDG_5315	clpP	LDG_5315	LDG_7718	ATP binding protease component ClpA; Belongs to the ClpA/ClpB family.	ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.969
LDG_5315	clpS	LDG_5315	LDG_5314	ATP binding protease component ClpA; Belongs to the ClpA/ClpB family.	Hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.	0.990
LDG_5315	dnaK	LDG_5315	LDG_5102	ATP binding protease component ClpA; Belongs to the ClpA/ClpB family.	Chaperone protein DnaK (heat shock 70 kDa protein,HSP70); Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.985
LDG_5315	groS	LDG_5315	LDG_6756	ATP binding protease component ClpA; Belongs to the ClpA/ClpB family.	Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	0.722
LDG_6135	LDG_8910	LDG_6135	LDG_8910	Hypothetical protein.	Chaperone protein ClpB.	0.976
LDG_6135	clpP	LDG_6135	LDG_7718	Hypothetical protein.	ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.973
LDG_6135	clpS	LDG_6135	LDG_5314	Hypothetical protein.	Hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.	0.932
LDG_6135	dnaK	LDG_6135	LDG_5102	Hypothetical protein.	Chaperone protein DnaK (heat shock 70 kDa protein,HSP70); Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.985
LDG_6135	groS	LDG_6135	LDG_6756	Hypothetical protein.	Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	0.722
LDG_7719	clpP	LDG_7719	LDG_7718	Hypothetical protein.	ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.995
LDG_7719	clpX	LDG_7719	LDG_7720	Hypothetical protein.	ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.	0.773
LDG_7719	tig	LDG_7719	LDG_7717	Hypothetical protein.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.641
LDG_8910	LDG_6135	LDG_8910	LDG_6135	Chaperone protein ClpB.	Hypothetical protein.	0.976
LDG_8910	LDG_8911	LDG_8910	LDG_8911	Chaperone protein ClpB.	Endopeptidase Clp ATP-binding chain B (ClpB); Belongs to the ClpA/ClpB family.	0.990
LDG_8910	clpP	LDG_8910	LDG_7718	Chaperone protein ClpB.	ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.974
LDG_8910	clpS	LDG_8910	LDG_5314	Chaperone protein ClpB.	Hypothetical protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.	0.932
LDG_8910	dnaK	LDG_8910	LDG_5102	Chaperone protein ClpB.	Chaperone protein DnaK (heat shock 70 kDa protein,HSP70); Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.985
LDG_8910	groS	LDG_8910	LDG_6756	Chaperone protein ClpB.	Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	0.722
LDG_8911	LDG_8910	LDG_8911	LDG_8910	Endopeptidase Clp ATP-binding chain B (ClpB); Belongs to the ClpA/ClpB family.	Chaperone protein ClpB.	0.990
LDG_8911	clpP	LDG_8911	LDG_7718	Endopeptidase Clp ATP-binding chain B (ClpB); Belongs to the ClpA/ClpB family.	ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.969

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