STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LDG_7894Hypothetical protein. (371 aa)    
Predicted Functional Partners:
LDG_6785
Hypothetical protein.
 
 0.999
LDG_7895
Pyruvate dehydrogenase E1 beta subunit.
 
 0.999
pdhA
Pyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
 0.998
LDG_9075
Lipoamide dehydrogenase.
 
 0.997
LDG_8156
Alpha-ketoglutarate decarboxylase.
 
 0.983
LDG_9077
Hypothetical protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.973
LDG_7928
2-methylcitrate synthase; Belongs to the citrate synthase family.
  
 0.949
LDG_7411
Hypothetical protein.
 
 0.948
LDG_8804
Hypothetical protein.
  
 0.936
sucC
Succinyl CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.934
Your Current Organism:
Legionella drancourtii
NCBI taxonomy Id: 658187
Other names: L. drancourtii LLAP12, Legionella drancourtii LLAP12, Legionella drancourtii str. LLAP12, Legionella drancourtii strain LLAP12
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.