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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LDG_79182-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK. (91 aa)    
Predicted Functional Partners:
LDG_8775
7,8-dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 
 0.996
LDG_5106
Dihydroneopterin aldolase FolB, putative kinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 
 0.989
folE
GTP cyclohydrolase I.
 
  
 0.956
LDG_7919
Poly(A) polymerase (PAP) (plasmid copy number protein); Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
    0.920
LDG_8930
Hypothetical protein.
 
 
 0.894
LDG_8877
FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family.
 
 
 0.872
ribBA
Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
 0.765
LDG_8544
4-amino-4-deoxychorismate lyase.
 
 
 0.714
LDG_7897
Para-aminobenzoate synthase, component I.
 
 
 0.712
ilvE
Hypothetical protein; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.639
Your Current Organism:
Legionella drancourtii
NCBI taxonomy Id: 658187
Other names: L. drancourtii LLAP12, Legionella drancourtii LLAP12, Legionella drancourtii str. LLAP12, Legionella drancourtii strain LLAP12
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