def-3 protein (Legionella drancourtii) - STRING interaction network

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def-3

Hypothetical protein; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (179 aa)

Predicted Functional Partners:

rplD

0.841

rplU

0.837

rplV

0.830

tig

0.827

rplI

0.827

rplT

0.826

rplQ

0.823

rpsP

0.820

rpsT

0.819

rpmA

0.817

Your Current Organism:

Legionella drancourtii

NCBI taxonomy Id: 658187
Other names: L. drancourtii LLAP12, Legionella drancourtii LLAP12, Legionella drancourtii str. LLAP12, Legionella drancourtii strain LLAP12

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
def-3	rplD	LDG_8600	LDG_8356	Hypothetical protein; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	0.841
def-3	rplI	LDG_8600	LDG_7866	Hypothetical protein; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	50S ribosomal protein L9; Binds to the 23S rRNA.	0.827
def-3	rplQ	LDG_8600	LDG_8379	Hypothetical protein; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	50S ribosomal protein L17.	0.823
def-3	rplT	LDG_8600	LDG_8238	Hypothetical protein; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.826
def-3	rplU	LDG_8600	LDG_8612	Hypothetical protein; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.837
def-3	rplV	LDG_8600	LDG_8360	Hypothetical protein; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	0.830
def-3	rpmA	LDG_8600	LDG_8613	Hypothetical protein; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.	0.817
def-3	rpsP	LDG_8600	LDG_8445	Hypothetical protein; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.	0.820
def-3	rpsT	LDG_8600	LDG_8641	Hypothetical protein; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.	0.819
def-3	tig	LDG_8600	LDG_7717	Hypothetical protein; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.827
rplD	def-3	LDG_8356	LDG_8600	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	Hypothetical protein; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.	0.841
rplD	rplI	LDG_8356	LDG_7866	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	50S ribosomal protein L9; Binds to the 23S rRNA.	0.997
rplD	rplQ	LDG_8356	LDG_8379	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	50S ribosomal protein L17.	0.997
rplD	rplT	LDG_8356	LDG_8238	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.996
rplD	rplU	LDG_8356	LDG_8612	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.995
rplD	rplV	LDG_8356	LDG_8360	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.	0.999
rplD	rpmA	LDG_8356	LDG_8613	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.	0.995
rplD	rpsP	LDG_8356	LDG_8445	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.	0.996
rplD	rpsT	LDG_8356	LDG_8641	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.	0.985
rplD	tig	LDG_8356	LDG_7717	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.	0.985

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