STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LDG_8989Hypothetical protein. (114 aa)    
Predicted Functional Partners:
LDG_8990
Putative poly-gamma-glutamate synthesis protein (capsule biosynthesis protein).
 
     0.804
guaA
Hypothetical protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.730
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.598
purA
Hypothetical protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.554
LDG_7939
Hypothetical protein.
  
 0.517
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.501
LDG_8681
Hypothetical protein.
    
 0.501
LDG_8863
Hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.457
LDG_7135
MazG (nucleoside triphosphate pyrophosphohydrolase).
     
  0.456
LDG_7985
Hypothetical protein.
     
  0.456
Your Current Organism:
Legionella drancourtii
NCBI taxonomy Id: 658187
Other names: L. drancourtii LLAP12, Legionella drancourtii LLAP12, Legionella drancourtii str. LLAP12, Legionella drancourtii strain LLAP12
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