| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LDG_9037 | cheB | LDG_9037 | LDG_6365 | Hypothetical protein. | Putative response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | 0.418 |
| LDG_9037 | ffh | LDG_9037 | LDG_8446 | Hypothetical protein. | Signal recognition particle protein Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual comp [...] | 0.407 |
| LDG_9037 | guaA | LDG_9037 | LDG_7848 | Hypothetical protein. | Hypothetical protein; Catalyzes the synthesis of GMP from XMP. | 0.615 |
| LDG_9037 | pyrH | LDG_9037 | LDG_9034 | Hypothetical protein. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.401 |
| LDG_9037 | secE | LDG_9037 | LDG_8342 | Hypothetical protein. | Hypothetical protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.406 |
| LDG_9037 | secY | LDG_9037 | LDG_8374 | Hypothetical protein. | Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.443 |
| LDG_9037 | tolB | LDG_9037 | LDG_7890 | Hypothetical protein. | TolB colicin import protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.563 |
| LDG_9037 | tolR | LDG_9037 | LDG_7888 | Hypothetical protein. | Hypothetical protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.462 |
| cheB | LDG_9037 | LDG_6365 | LDG_9037 | Putative response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | Hypothetical protein. | 0.418 |
| ffh | LDG_9037 | LDG_8446 | LDG_9037 | Signal recognition particle protein Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual comp [...] | Hypothetical protein. | 0.407 |
| ffh | pyrH | LDG_8446 | LDG_9034 | Signal recognition particle protein Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual comp [...] | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.694 |
| ffh | secE | LDG_8446 | LDG_8342 | Signal recognition particle protein Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual comp [...] | Hypothetical protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.957 |
| ffh | secY | LDG_8446 | LDG_8374 | Signal recognition particle protein Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual comp [...] | Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.965 |
| guaA | LDG_9037 | LDG_7848 | LDG_9037 | Hypothetical protein; Catalyzes the synthesis of GMP from XMP. | Hypothetical protein. | 0.615 |
| guaA | pyrH | LDG_7848 | LDG_9034 | Hypothetical protein; Catalyzes the synthesis of GMP from XMP. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.764 |
| pyrH | LDG_9037 | LDG_9034 | LDG_9037 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Hypothetical protein. | 0.401 |
| pyrH | ffh | LDG_9034 | LDG_8446 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Signal recognition particle protein Ffh; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual comp [...] | 0.694 |
| pyrH | guaA | LDG_9034 | LDG_7848 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Hypothetical protein; Catalyzes the synthesis of GMP from XMP. | 0.764 |
| pyrH | secY | LDG_9034 | LDG_8374 | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.445 |
| secE | LDG_9037 | LDG_8342 | LDG_9037 | Hypothetical protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | Hypothetical protein. | 0.406 |
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