node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDZ76903.1 | SDZ91987.1 | SAMN05216562_0165 | SAMN05216562_1208 | NADPH-glutathione reductase; Maintains high levels of reduced glutathione. | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.912 |
SDZ76903.1 | SDZ92008.1 | SAMN05216562_0165 | SAMN05216562_1209 | NADPH-glutathione reductase; Maintains high levels of reduced glutathione. | 2-oxoglutarate dehydrogenase E1 component. | 0.916 |
SDZ76903.1 | SEA17599.1 | SAMN05216562_0165 | SAMN05216562_2123 | NADPH-glutathione reductase; Maintains high levels of reduced glutathione. | Pyruvate dehydrogenase E1 component beta subunit. | 0.977 |
SDZ76903.1 | SEA22687.1 | SAMN05216562_0165 | SAMN05216562_2380 | NADPH-glutathione reductase; Maintains high levels of reduced glutathione. | Glutamate synthase (NADPH/NADH) large chain. | 0.876 |
SDZ76903.1 | pdhA | SAMN05216562_0165 | SAMN05216562_2124 | NADPH-glutathione reductase; Maintains high levels of reduced glutathione. | Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.926 |
SDZ79432.1 | SDZ91987.1 | SAMN05216562_0356 | SAMN05216562_1208 | NAD(P) transhydrogenase. | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.955 |
SDZ79432.1 | SDZ92008.1 | SAMN05216562_0356 | SAMN05216562_1209 | NAD(P) transhydrogenase. | 2-oxoglutarate dehydrogenase E1 component. | 0.940 |
SDZ79432.1 | SEA17599.1 | SAMN05216562_0356 | SAMN05216562_2123 | NAD(P) transhydrogenase. | Pyruvate dehydrogenase E1 component beta subunit. | 0.969 |
SDZ79432.1 | SEA22687.1 | SAMN05216562_0356 | SAMN05216562_2380 | NAD(P) transhydrogenase. | Glutamate synthase (NADPH/NADH) large chain. | 0.876 |
SDZ79432.1 | pdhA | SAMN05216562_0356 | SAMN05216562_2124 | NAD(P) transhydrogenase. | Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.906 |
SDZ79432.1 | sucC | SAMN05216562_0356 | SAMN05216562_1206 | NAD(P) transhydrogenase. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.446 |
SDZ91846.1 | SDZ91987.1 | SAMN05216562_1200 | SAMN05216562_1208 | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component. | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.917 |
SDZ91846.1 | SDZ92008.1 | SAMN05216562_1200 | SAMN05216562_1209 | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component. | 2-oxoglutarate dehydrogenase E1 component. | 0.921 |
SDZ91846.1 | SEA17599.1 | SAMN05216562_1200 | SAMN05216562_2123 | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component. | Pyruvate dehydrogenase E1 component beta subunit. | 0.972 |
SDZ91846.1 | SEA22687.1 | SAMN05216562_1200 | SAMN05216562_2380 | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component. | Glutamate synthase (NADPH/NADH) large chain. | 0.880 |
SDZ91846.1 | pdhA | SAMN05216562_1200 | SAMN05216562_2124 | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component. | Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.916 |
SDZ91846.1 | sucC | SAMN05216562_1200 | SAMN05216562_1206 | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.427 |
SDZ91970.1 | SDZ91987.1 | SAMN05216562_1207 | SAMN05216562_1208 | Dihydrolipoamide dehydrogenase. | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.998 |
SDZ91970.1 | SDZ92008.1 | SAMN05216562_1207 | SAMN05216562_1209 | Dihydrolipoamide dehydrogenase. | 2-oxoglutarate dehydrogenase E1 component. | 0.990 |
SDZ91970.1 | SEA17599.1 | SAMN05216562_1207 | SAMN05216562_2123 | Dihydrolipoamide dehydrogenase. | Pyruvate dehydrogenase E1 component beta subunit. | 0.990 |