node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDZ83989.1 | SDZ96877.1 | SAMN05216562_0683 | SAMN05216562_1460 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Serine O-acetyltransferase. | 0.941 |
SDZ83989.1 | SEA31201.1 | SAMN05216562_0683 | SAMN05216562_2559 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Threonine dehydratase. | 0.949 |
SDZ83989.1 | SEA42499.1 | SAMN05216562_0683 | SAMN05216562_3069 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Phosphoserine phosphatase. | 0.962 |
SDZ83989.1 | SEA42688.1 | SAMN05216562_0683 | SAMN05216562_3079 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Serine O-acetyltransferase. | 0.941 |
SDZ83989.1 | glyA | SAMN05216562_0683 | SAMN05216562_3210 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.972 |
SDZ83989.1 | serC | SAMN05216562_0683 | SAMN05216562_0852 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.612 |
SDZ83989.1 | trpA | SAMN05216562_0683 | SAMN05216562_1111 | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.939 |
SDZ96877.1 | SDZ83989.1 | SAMN05216562_1460 | SAMN05216562_0683 | Serine O-acetyltransferase. | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.941 |
SDZ96877.1 | SEA42499.1 | SAMN05216562_1460 | SAMN05216562_3069 | Serine O-acetyltransferase. | Phosphoserine phosphatase. | 0.937 |
SDZ96877.1 | SEA42688.1 | SAMN05216562_1460 | SAMN05216562_3079 | Serine O-acetyltransferase. | Serine O-acetyltransferase. | 0.940 |
SDZ96877.1 | glyA | SAMN05216562_1460 | SAMN05216562_3210 | Serine O-acetyltransferase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.859 |
SDZ96877.1 | metXS | SAMN05216562_1460 | SAMN05216562_2335 | Serine O-acetyltransferase. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.403 |
SDZ96877.1 | trpA | SAMN05216562_1460 | SAMN05216562_1111 | Serine O-acetyltransferase. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.845 |
SDZ96877.1 | trpB | SAMN05216562_1460 | SAMN05216562_1112 | Serine O-acetyltransferase. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.843 |
SEA31201.1 | SDZ83989.1 | SAMN05216562_2559 | SAMN05216562_0683 | Threonine dehydratase. | L-serine ammonia-lyase; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.949 |
SEA31201.1 | SEA42499.1 | SAMN05216562_2559 | SAMN05216562_3069 | Threonine dehydratase. | Phosphoserine phosphatase. | 0.942 |
SEA31201.1 | SEA47580.1 | SAMN05216562_2559 | SAMN05216562_3272 | Threonine dehydratase. | CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.938 |
SEA31201.1 | glyA | SAMN05216562_2559 | SAMN05216562_3210 | Threonine dehydratase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.944 |
SEA31201.1 | metXS | SAMN05216562_2559 | SAMN05216562_2335 | Threonine dehydratase. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.855 |
SEA31201.1 | trpA | SAMN05216562_2559 | SAMN05216562_1111 | Threonine dehydratase. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.948 |