STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GMDG_01147Zn(2)-C6 fungal-type domain-containing protein. (774 aa)    
Predicted Functional Partners:
GMDG_01924
FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]
   
  0.860
GMDG_07117
Uncharacterized protein.
    
  0.856
GMDG_07650
CMGC/CK2 protein kinase.
   
 0.854
MDM34
Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
   
 0.854
GMDG_06857
Uncharacterized protein.
    
 0.811
GMDG_04651
U3 small nucleolar RNA-associated protein 22.
    
 0.800
GMDG_00816
Uncharacterized protein.
    
  0.774
GMDG_06565
WD_REPEATS_REGION domain-containing protein.
   
 
 0.629
GMDG_08332
RNA helicase.
    
   0.601
GMDG_03096
S4 RNA-binding domain-containing protein.
   
   0.593
Your Current Organism:
Pseudogymnoascus destructans
NCBI taxonomy Id: 658429
Other names: Geomyces destructans 20631-21, P. destructans 20631-21, Pseudogymnoascus destructans 20631-21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.