STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GMDG_06758Uncharacterized protein. (378 aa)    
Predicted Functional Partners:
GMDG_07706
Malate synthase; Belongs to the malate synthase family.
   
 
 0.879
GMDG_05686
Citrate synthase; Belongs to the citrate synthase family.
  
 0.831
GMDG_05820
Citrate synthase; Belongs to the citrate synthase family.
  
 0.831
GMDG_00679
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.805
GMDG_06357
Acetyl-CoA carboxylase/biotin carboxylase.
  
 
 0.768
GMDG_08254
Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.765
GMDG_00729
Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.765
GMDG_00033
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 
 0.761
GMDG_03369
Aminotran_5 domain-containing protein.
  
 
 0.755
GMDG_06903
2-isopropylmalate synthase.
  
 
 0.752
Your Current Organism:
Pseudogymnoascus destructans
NCBI taxonomy Id: 658429
Other names: Geomyces destructans 20631-21, P. destructans 20631-21, Pseudogymnoascus destructans 20631-21
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