STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GMDG_02437Uncharacterized protein. (284 aa)    
Predicted Functional Partners:
GMDG_01424
Uncharacterized protein.
   
 0.996
GMDG_04233
RRM domain-containing protein.
   
 
 0.990
GMDG_04725
Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site; Belongs to the snRNP core protein family.
    
 
 0.979
GMDG_04082
U2 small nuclear ribonucleoprotein A.
    
 0.975
GMDG_06347
Nuclear cap-binding protein subunit 2.
    
 
 0.971
GMDG_04151
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
    
 0.967
GMDG_05915
Uncharacterized protein.
    
 0.959
GMDG_02326
Uncharacterized protein.
   
 0.955
GMDG_06935
Uncharacterized protein.
   
 
 0.954
GMDG_02421
WW domain-containing protein.
   
  0.946
Your Current Organism:
Pseudogymnoascus destructans
NCBI taxonomy Id: 658429
Other names: Geomyces destructans 20631-21, P. destructans 20631-21, Pseudogymnoascus destructans 20631-21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.