node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GMDG_00235 | GMDG_00833 | L8FWW5 | L8GE36 | Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.519 |
GMDG_00235 | GMDG_06268 | L8FWW5 | L8FT26 | Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. | Nucleoside diphosphate kinase. | 0.561 |
GMDG_00235 | GMDG_06401 | L8FWW5 | L8FT86 | Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. | 0.424 |
GMDG_00235 | GMDG_06791 | L8FWW5 | L8FU42 | Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. | Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. | 0.758 |
GMDG_00235 | GMDG_08507 | L8FWW5 | L8G3G0 | Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. | Uncharacterized protein. | 0.794 |
GMDG_00833 | GMDG_00235 | L8GE36 | L8FWW5 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. | 0.519 |
GMDG_00833 | GMDG_01814 | L8GE36 | L8FYL5 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. | 0.759 |
GMDG_00833 | GMDG_04865 | L8GE36 | L8GD36 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | A_deaminase domain-containing protein. | 0.787 |
GMDG_00833 | GMDG_06268 | L8GE36 | L8FT26 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Nucleoside diphosphate kinase. | 0.881 |
GMDG_00833 | GMDG_06401 | L8GE36 | L8FT86 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. | 0.777 |
GMDG_00833 | GMDG_08507 | L8GE36 | L8G3G0 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Uncharacterized protein. | 0.769 |
GMDG_01814 | GMDG_00833 | L8FYL5 | L8GE36 | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.759 |
GMDG_01814 | GMDG_04865 | L8FYL5 | L8GD36 | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. | A_deaminase domain-containing protein. | 0.740 |
GMDG_01814 | GMDG_06098 | L8FYL5 | L8FUC9 | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. | Phosphodiesterase. | 0.733 |
GMDG_01814 | GMDG_06268 | L8FYL5 | L8FT26 | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. | Nucleoside diphosphate kinase. | 0.733 |
GMDG_01814 | GMDG_06401 | L8FYL5 | L8FT86 | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. | 0.886 |
GMDG_01814 | GMDG_08507 | L8FYL5 | L8G3G0 | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. | Uncharacterized protein. | 0.786 |
GMDG_03899 | GMDG_07254 | L8G9K5 | L8FZW3 | Uncharacterized protein. | Uncharacterized protein. | 0.809 |
GMDG_03899 | GMDG_08507 | L8G9K5 | L8G3G0 | Uncharacterized protein. | Uncharacterized protein. | 0.905 |
GMDG_04865 | GMDG_00833 | L8GD36 | L8GE36 | A_deaminase domain-containing protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.787 |