STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GMDG_00619Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (409 aa)    
Predicted Functional Partners:
GMDG_00926
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.999
GMDG_02349
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.998
GMDG_01949
Uncharacterized protein.
  
 0.994
GMDG_01664
2-oxoisovalerate dehydrogenase E1 component, beta subunit.
 
 0.993
GMDG_04643
Dihydrolipoyl dehydrogenase.
   
 0.989
GMDG_03805
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.919
GMDG_03157
Dihydrolipoyllysine-residue succinyltransferase, E2 component.
  
 0.912
GMDG_03398
Oxoglutarate dehydrogenase, E1 component.
   
 0.912
GMDG_02082
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.
   
 0.900
GMDG_03248
Protein-serine/threonine kinase.
    
 0.895
Your Current Organism:
Pseudogymnoascus destructans
NCBI taxonomy Id: 658429
Other names: Geomyces destructans 20631-21, P. destructans 20631-21, Pseudogymnoascus destructans 20631-21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.