STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GMDG_04792ATP-dependent RNA helicase eIF4A; Belongs to the DEAD box helicase family. (398 aa)    
Predicted Functional Partners:
TIF34
Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
   
 
 0.985
GMDG_01304
Translation initiation factor eIF-4E; Belongs to the eukaryotic initiation factor 4E family.
   
 0.981
GMDG_02786
Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.
   
 0.972
PRT1
Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.
   
 
 0.970
GMDG_02684
40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.
   
 0.967
GMDG_04678
MIF4G domain-containing protein.
   
 0.963
GMDG_01408
Elongation factor 2.
   
 0.958
GMDG_05785
Guanine nucleotide-binding protein subunit beta-like protein.
   
 
 0.957
GMDG_01249
S1 motif domain-containing protein.
   
 0.957
GMDG_04900
RRM domain-containing protein.
   
 0.954
Your Current Organism:
Pseudogymnoascus destructans
NCBI taxonomy Id: 658429
Other names: Geomyces destructans 20631-21, P. destructans 20631-21, Pseudogymnoascus destructans 20631-21
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.