STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhADehydrogenase, E1 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (676 aa)    
Predicted Functional Partners:
AJR05448.1
Putative dehydrogenase catalytic domain-containing protein; COG0508.
 
 0.999
AJR05656.1
Dihydrolipoamide dehydrogenase; COG1249.
 
 0.999
AJR05883.1
Branched-chain alpha-keto acid dehydrogenase subunit E2; COG0508.
 
 0.999
AJR07452.1
Dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.999
AJR07937.1
Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.999
AJR07265.1
Dihydrolipoamide dehydrogenase; COG1249.
 
 0.998
AJR07453.1
Dihydrolipoamide dehydrogenase; COG1249.
 
 0.998
AJR08969.1
Hypothetical protein; COG1249.
 
 0.994
pdhA-2
Putative pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 
0.988
AJR07113.1
Glutathione reductase; COG1249.
 
 0.988
Your Current Organism:
Photobacterium gaetbulicola
NCBI taxonomy Id: 658445
Other names: P. gaetbulicola Gung47, Photobacterium gaetbulicola Gung47, Photobacterium sp. Gung47
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